Working to break out of this typecasting, Collins eventually gained greater recognition in a role opposite Samuel L. Jackson in 1997's One Eight Seven. He went on to play a variety of characters in films including The Replacement Killers, The Wonderful Ice Cream Suit, Tigerland, Traffic and Mind Hunters.
Television work has included appearances on "NYPD Blue," "The Twilight Zone," "Resurrection Blvd." and "Alias." In 2005, Collins gave a critically acclaimed performance as the object of Truman Capote's obsession in the multiple Oscar-winning film Capote, and in 2006, he received an Emmy nod for his work on the FX series "Thief."