Touted as a rising star in the media, Renfro nabbed lead roles in Tom and Huck (1995), Sleepers (1996) and Apt Pupil (1998). But as the actor moved from adolescence into adulthood, he gravitated toward supporting roles in more independent fare such as Ghost World (2001).
Renfro died on Jan. 15, 2008, at the age of 25, during the filming of The Informers (2008). His death was somewhat overshadowed by fellow actor Heath Ledger's demise exactly one week later.