Born June 29, 1944, in Goose Creek, Texas, Busey spent time on an Oklahoma ranch growing up, learning to ride bulls and acquiring the other cowboy skills that would help land him his debut role in the TV Western "The High Chaparral." After receiving an Oscar nod for his work in The Buddy Holly Story, Busey continued to land important films during the 1970s and '80s, including Big Wednesday and Lethal Weapon.
In more recent years, Busey has played the villain to perfection in films such as Hider in the House (1989) and Under Siege (1992). In 2006, he lent his voice to Dr. Dolittle 3.