When two married couples meet in a hospital emergency room, their lives become inexplicably intertwined. Despite having a son, Elena (Maribel Verdú) and Chus (Jorge Sanz) have continued to drift apart, while tragedy has damaged Sara (Maria Barranco) and Oscar's (Dario Grandinetti) relationship beyond repair. Unfortunately, the platonic friendship that forms between Sara and Chus is no match for the passion that flares between Elena and Oscar.