When a quartet of hot-air balloonists headed by scientist Paul Hadley (Robert Clarke) crash-lands on a remote isle, they find a relative of Dr. Frankenstein carrying on the family tradition of conducting monstrous experiments. Marooned on the island with zombies, nubile jungle girls, a pie-eyed sea salt (Steve Brodie), a race of Amazons, a demented sea captain (Cameron Mitchell) and a disembodied brain, will the stranded crew ever make it home?

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