In Tennessee Williams's tale of sexual repression set in 1937 New Orleans, rich widow Mrs. Venable (Katharine Hepburn) is distraught over the death of her son Sebastian during his vacation to Europe, where the two had traveled together every summer. This time, Sebastian had taken his cousin Catherine (Elizabeth Taylor), who appears to go mad the day Sebastian dies. Dr. Cukrowicz (Montgomery Clift) is called in to assess her mental state.

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